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BodyText Sequence Analysis
- dCAPS Finder
(Mismatch PCR Primer Design Tool) A program from Washington University to design mismatch PCR primers for the detection of SNP's by simple restriction enzyme digestion and electrophoresis. The web-based program is described by Neff, Turk , & Kalishman TIGS 18:613-15, 2002.
- SSCP Analysis
Access to new software, QUISCA, for the analysis of capillary array SSCP data (free for academic users!) from Professor Hayashi's laboratory. QUISCA is Quantitative Interpretation of SSCP in Capillary Array and is described in BioTechniques 33:1342-8, 2002.
- Searching GenBank
Search GenBank, dbEST (expressed sequence tag database) dbSTS (sequence tagged site database), or dbGSS (genome survey sequences database).
- Pedro's BioMolecular Research Tools
Jump station to a long list of useful Internet accessible sequence analysis programs for nucleic acid and protein sequences.
- BioToolkit
Jump station to Internet servers- 3 categories, Nucleic Acid Analysis, Genome Resourses, and Protein Structural Imaging and Analysis.
- BLAST
Search the public databases for homology to any sequence using BLAST.
- ExPASY
ExPASy (Expert Protein Analysis System) is the proteomics server of the Swiss Institute of Bioinformatics (SIB) dedicated to the analysis of protein sequences and structures as well as 2-D PAGE
- Database and Search Tools
(Formerly known as the Biologist's Control panel). Jump station to useful tools at Baylor College of Medicine.
Genomics
- UniGene
UniGene is an experimental system for automatically partitioning GenBank sequences into a non-redundant set of gene-oriented clusters.
- I.M.A.G.E
The Integrated Molecular Analysis of Genomes and their Expression Consortium is a public collection of cloned genes and ESTs
- Genome Database
GDB is the central repository for genomic mapping data resulting from the Human Genome Initiative.
- Genome Gateway
A comprehensive web resource devoted to genomics maintained by the Nature publishing Group.
- Human Genome Project Information
Educational site about the Human Genome Project at the DOE site.
- Genomics Glossaries
A very nice set of glossaries for Genomics, Pharmacogenomics, Proteomics, and Structural Biology. At the Cambridge Healthtech Institute (CHI) site. Use the buttons on the right of the frame to go to the Genomic Glossaries.
Genetics
- The Lieden Muscular Dystrophy page
This site contains a lot of useful information on the genes and proteins involved in hereditary muscular dystrophy. Includes mutation/polymorphism databases and detailed protocols for molecular analyses.
- OMIM
Online Mendelian Inhertance in Man (OMIM) is a comprehensive survey of the literature with information on genes and genetic disorders.
- GeneTests
Listing of clinical laboratories offering genetic testing.
- Human Mutation Database
The Human Gene Mutation Database (HGMD) represents an attempt to collate known (published) gene lesions responsible for human inherited disease with links to many locus specific databases.
- Cystic Fibrosis Mutation Database
Compilation of mutations in the CFTR gene maintained by Dr. Lap-Chee Tsui.
- DNA Learning Center
Introduction to DNA and genetics at Cold Spring Harbor Laboratory.
- Breast Cancer Information Core
Compilation of mutations (and methods) associated with inherited forms of breast cancer.
- The National Tay-Sachs & Allied Diseases Association
(NTSAD ) is dedicated to the treatment and prevention of Tay-Sachs and related diseases, and to provide information and support services to individuals and families affected by these diseases, as well as the public at large.
- Secretary's Advisory Committee on Genetic Testing
- American Medical Association Genetics and Molecular Medicine page
Excellent resource for educational materials. Policies of the AMA regarding a number of issues pertaining to Medical Genetics.
- CAP Sample Exchange Registry
The CAP Sample Exchange Registry for Alternative Assessment is an Internet-based service designed to connect laboratories performing esoteric genetic testing where no formal proficiency testing is available. When at least three laboratories are identified as testing for the same genetic disorder, the CAP will facilitate the sample exchange.
Statistics
- Statistics Calculators
I don't know who john71 is, but he maintains one of the most useful collection of statistical calculators and tutorials on the web! Never do a manual Chi Square calculation again!
Pharmocogenetics and Pharmocogenomics
Metabolic Pathways
- Boehringer Mannheim "Biochemical Pathways"
This page gives access to the digitized version of the Boehringer Mannheim "Biochemical Pathways" wall chart at the ExPASy site.
- EcoCyc
EcoCyc is a metabolic-pathway database. The database describes pathways, reactions, and enzymes of a variety of organisms, with a microbial focus.
- MetaCyc
MetaCyc contains the E. coli pathways of EcoCyc, plus additional pathways that have been gathered from a variety of literature and on-line sources, with citations to the source of each pathway.
Cancer
- OncoLink
Founded in 1994 by Penn cancer specialists with a mission to help cancer patients, families, health care professionals and the general public get accurate cancer-related information at no charge.
- The Cancer Genome Anatomy Project
(CGAP) is an interdisciplinary program established and administered by the National Cancer Institute to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell.
HIV
- AIDS Knowledge Base
An on-line textbook on HIV disease from the University of California, San Francisco and San Francisco General Hospital
- HIV Sequence Database
A database maintained at Los Alamos National Laboratories of HIV genome sequences, including an on-line tool for the identification of drug resistance mutations in user submitted sequence.
- Stanford HIV RT and Protease Sequence Database
An on-line tool for the identification of drug resistance mutations in user submitted sequence.
HCV
- CDC
Hepatitis homepage . Educational site on hepatitis at the CDC
Microarray Technology
- DRAGON
Online software for the annotation and analysis of microarray data from the Professor Prevsner's lab at the Kennedy-Kreiger Isntitute. DRAGON is Database Referencing of Array Genes Online.
- Brown Lab Homepage
Homepage for one of the guru's of the field- includes instructions for building your own arrayer!
- Gene-Chips.com
You'll find the basics on DNA microarray technology and a list of academic and industrial links related to this exciting new technology.
- NHGRI Microarray page
About microarray research at NHGRI
- Papers on Microarrays
List of papers maintained by Wentian Li, Rockefeller University.
- TIGR Protocols
Microarray protocols from The Institute for Genome Research
Organizations
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