Case Study - NACB Blog

4/16/2013 2:17 PM | Comments (0) Recommend (118)

By William E. Winter, MD; Roger L. Bertholf, Ph.D.

Challenge: I was recently asked what medical concerns exist for people with autoimmune diabetes [either type 1 diabetes or latent autoimmune diseases of adulthood (LADA)] that are not shared by people with type 2 diabetes. Certainly for all people with diabetes of any kind, attempting to achieve...(Read More)

Posted at 4/16/2013 2:17 PM | Tags: Case Study | Diabetes/Endocrinology

Where Is the Hemoglobin S?

4/2/2013 2:52 PM | Comments (0) Recommend (139)

By William E. Winter, MD; Lindsay Bazydlo, PhD, and Neil S. Harris, MD

Case: The patient was an African American woman between the ages of 30 and 40 years. She previously had a gastric bypass and lost weight from 400 lbs to less than 200 lbs. Since that time the patient suffered from multiple episodes of ill defined abdominal pain, vomiting and diarrhea attributed, i...(Read More)

Posted at 4/2/2013 2:52 PM | Tags: Case Study | TDM/Toxicology

Is This A Straight Trait (AS) or Are We All Wet?

3/5/2013 9:32 AM | Comments (0) Recommend (223)

By William E. Winter, MD; Lindsay Bazydlo, PhD, and Neil S. Harris, MD

Challenge: The patient is a 16 month old male. How should the results of the following hemoglobin electrophoresis be interpreted? By alkaline gel electrophoresis: 59.5% hemoglobin A0.6% hemoglobin F36.6% hemoglobin S By cation-exchange HPLC BioRad D-10 (Extended Program): hemoglobin A2 ...(Read More)

Posted at 3/5/2013 9:32 AM | Tags: Case Study | Molecular Pathology and Genetics

A preanalytical problem or something more!

2/5/2013 4:45 PM | Comments (1) Recommend (462)

By Sutirtha Chakraborty, MD & William Winter, MD, DABCC, FACB

Case: A member of the technical staff informed the author that he had encountered a problematic sample. The technician stated that on centrifuging the sample (that had been collected in a gel vacutainer tube), proper separation of the cells and the serum did not occur (Figure 1, left side). He was...(Read More)

Posted at 2/5/2013 4:45 PM | Tags: Case Study | Instrumentation/Technology

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