American Association for Clinical Chemistry
Improving healthcare through laboratory medicine
 

Clinical Chemistry Podcasts

Check back often for the latest podcasts highlighting selected articles. Some segments have been broadcast on The Health Show and may be heard at their web site.*

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In Print
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Vitamin D and cancer: Can we believe the evidence from observational studies?Cook, Nancy13:58
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Circulating microRNAs: What is their relevance?Hilton, Catriona8:24
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Molecular detection of human H7N9 influenza A virus causing outbreaks in ChinaPoon, Leo6:45
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Targeting the Circulating MicroRNA Signature of ObesityOrtega, Francisco José12:18
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Pharm-Econogenomics: A New AppraisalTopol, Eric6:10
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May Audio Summary7:51
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The Human Gut Microbiome and Body Metabolism: Implications for Obesity and DiabetesVersalovic, James23:26
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Q&A on PheochromocytomaEstey, Mathew, and Eisenhofer, Graeme20:50
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Mobile Device for Disease Diagnosis and Data Tracking in Resource-Limited SettingsSia, Samuel15:44
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Predicting the Cost and Pace of Pharmacogenomic Advances: An Evidence-Based StudyArnaout, Ramy9:05
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April 2013 Audio Summary8:51
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Male Infertility and MicrochipsPark, Jason7:44
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Cannabis Effects on Driving SkillsHartman, Rebecca and Huestis, Marilyn22:18
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Low Plasma 25-Hydroxyvitamin D and Risk of Tobacco-Related CancerNordestgaard, Børge10:30
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More Data, Please!Baggerly, Keith17:40
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MALDI-TOF Mass Spectrometry: Transformative Proteomics for Clinical MicrobiologyPatel, Robin4:48
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March 2013 Audio Summary7:41
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Is Early Detection of Cancer with Circulating Biomarkers Feasible?Konforte, Danijela14:23
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February 2013 Audio Summary7:30
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External Quality Assessment of Point-of-Care Methods: Model For Combined Assessment of Method Bias and Single-Participant Performance by the Use of Native Patient Samples and Noncommutable Control MaterialStavelin, Anne10:43
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MicroRNA Analysis: Is It Ready for Prime Time?Tsongalis, Gregory8:59
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Commercial Immunoassays in Biomarkers Studies: Researchers Beware!Rifai, Nader8:27
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Data Submission and Quality in Microarray-Based MicroRNA ProfilingWitwer, Kenneth11:56
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Comparing Multiple Measures of Glycemia: How to Transition from Biomarker to Diagnostic Test?Cohen, Robert and Sacks, David18:45
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January 2013 Audio Summary12:31
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The Riddle of Protein Diagnostics: Future Bleak or Bright?Anderson, Leigh8:53
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Conquering Cancer in Our Lifetime: New Diagnostic and Therapuetic TrendsDiamandis, Eleftherios9:25
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Plasma-Derived Tumor DNA Analysis at Whole-Genome ResolutionSwanton, Charles12:19
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Validating serum markers for monitoring of cancerStenman, Ulf-Hakan5:07
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Design of Tumor Biomarker-Monitoring Trials: A Proposal by the European Group on Tumor MarkersSölétormos, György11:37
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Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing Lo, Dennis5:07
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Associations of Alternative Markers of Glycemia with Hemoglobin A1c and Fasting GlucoseSelvin, Elizabeth4:14
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The Evolving Threat of Influenza Viruses of Animal Origin and the Challenges in Developing Appropriate DiagnosticsPoon, Leo LM8:25
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Quantitative PCR Analysis of DNA, RNAs, and Proteins in the Same Single CellStåhlberg, Anders12:40
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Performance Criteria for Testosterone Measurements Based on Biological Variation in Adult Males: Recommendations from the Partnership for the Accurate Testing of HormonesFitzgerald, Robert L9:42
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Medicine Unplugged: The Future of Laboratory MedicineTopol, Eric J.8:32
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December 2012 Audio Summary6:59
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Longitudinal Studies of Cardiac Troponin I in a Large Cohort of Healthy ChildrenHickman, Peter E.11:04
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Determination of 19 Cardiac Troponin I and T Assay 99th Percentile Values from a Common Presumably Healthy PopulationApple, Fred S.14:52
On-Site Test for Cannabinoids in Oral Fluid*Desrosiers, Nathalie A. and Marilyn A. Huestis16:08
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November 2012 Audio Summary5:32
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Ectopic PregnancyShaw, Julie L.V. and Andrew W. Horne6:28
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Exome and Whole-Genome Sequencing as Clinical Tests: A Transformative Practice in Molecular DiagnosticsShen, Yiping10:28
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More Reliable On-Site Detection of Cannabis in Oral FluidVerstraete, Alain G6:36
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Room for Improvement in National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines*Bossuyt, Patrick M.M.5:34
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Applicability of the AGREE II Instrument in Evaluating the Development Process and Quality of Current National Academy of Clinical Biochemistry GuidelinesDon-Wauchope, Andrew C.08:24
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Noninvasive Prenatal Diagnosis of Monogenic Diseases by Targeted Massively Parallel Sequencing of Maternal Plasma: Application to β-ThalassemiaLo, Y.M. Dennis5:43
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The Human Salivary RNA Transcriptome Revealed by Massively Parallel SequencingWong, David T.W.15:10
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Caution Is Needed in the Interpretation of Added Value of Biomarkers Analyzed in Matched Case Control StudiesPencina, Michael J.11:50
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Whole-Blood Thrombin Generation Monitored with a Calibrated Automated Thrombogram-Based AssayHemker, H. Coenraad07:24
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Thyroid Function during Pregnancy: Who and How Should We Screen?*Gronowski, Ann M. & Haddow, James22:39
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Interpreting Cardiac Troponin Results from High-Sensitivity Assays in Chronic Kidney Disease without Acute Coronary SyndromedeFilippi, Christopher9:02
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Antibiotic Resistance: How Serious Is the Problem, and What Can Be Done?*McAdam, Alexander J.12:22
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Circulating Human Hepcidin-25 Concentrations Display a Diurnal Rhythm, Increase with Prolonged Fasting, and Are Reduced by Growth Hormone AdministrationKonrad, Robert J.7:52
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Establishing Pediatric Reference Intervals: A Challenging TaskCeriotti, Ferruccio7:59
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A Unique Approach to Business Strategy as a Means to Enable Change in Global Healthcare: A Case StudyRyan, Una S10:27
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The Obesity Epidemic*Shea, Jennifer11:30
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Newer Fecal Tests: Opportunities for Professionals in Laboratory MedicineFraser, Callum12:56
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Diagnostic Accuracy of Point-of-Care Fecal Calprotectin and Immunochemical Occult Blood Tests for Diagnosis of Organic Bowel Disease in Primary Care: The Cost-Effectiveness of a Decision Rule for Abdominal Complaints in Primary Care (CEDAR) StudyKok, Liselotte7:08
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Altering the Landscape for Women in Clinical Chemistry: Perspectives from Multigenerational LeadersHaymond, Shannon6:42
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Clinician’s Perspective: Allan JaffeJaffe, Allan14:37
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Elementary, My Dear Doctor Watson*Arnaout, Ramy10:29
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Patents and Laboratory Medicine: What Is Required to Turn an Unpatenable Natural Phenomenon or Law of Nature into a Patenable Invention?Powlick, Jill10:38
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Inappropriate Requesting of Glycated Hemoglobin (Hb A1c) Is Widespread: Assessment of Prevalence, Impact of National Guidance, and Practice-to-Practice VariabilityFryer, Anthony35:21
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Genetic Susceptibility for Coronary Heart Disease and Type 2 Diabetes ComplicationsHarrison, Seamus7:44
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Catch Me If You Can: Isolating Circulating Tumor Cells from Flowing BloodNeeves, Keith6:32
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Closing the Gaps in Pediatric Laboratory Reference Intervals: A CALIPER Database of 40 Biochemical Markers in a Healthy and Multiethnic Population of ChildrenAdeli, Khosrow19:15
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Microtube Device for Selectin-Mediated Capture of Viable Circulating Tumor Cells from BloodKing, Michael6:29
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Fluorescence Sensor for the Quantification of Unbound Bilirubin ConcentrationsKleinfeld, Alan10:37
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Understanding the Mechanisms That Link Alcohol and Lower Risk of Coronary Heart DiseaseMukamal, Kenneth24:11
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Refining Noninvasive Prenatal Diagnosis with Single-Molecule Next-Generation SequencingAvent, Neil5:08
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Point/Counterpoint: Standardization of Cardiac Troponin IChristenson, Rob & Apple, Fred22:44
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Discerning Trends in Multiplex Immunoassay Technology with Potential for Resource-Limited SettingsGordon, Julian11:13
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Single Molecule Sequencing of Free DNA from Maternal Plasma for Noninvasive Trisomy 21 DetectionBoon, Elles4:31
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Reference Measurement Procedure for Total Glycerides by Isotope Dilution GC-MSEdwards, Selvin8:49
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Personalized Cancer Genomics: The Road Map to Clinical ImplementationYousef, George M.12:39
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How Well Are We Training the Next Generation of Clinical Pathologists and Clinical Laboratory Directors? A Global PerspectiveScott, Mitch14:10
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Accuracy of 6 Routine 25-Hydroxyvitamin D Assays: Influence of Vitamin D Binding Protein ConcentrationHeijboer, Annemieke07:23
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Fragile X Mental Retardation 1 (FMR1) Intron 1 Methylation in Blood Predicts Verbal Cognitive Impairment in Female Carriers of Expanded FMR1 Alleles: Evidence from a Pilot StudyGodler, David13:02

 

 
Exhaled Endogenous Particles Contain Lung ProteinsBredberg, Ana5:51

 

 
Searching for New Biomarkers of Renal Diseases through ProteomicsKonvalinka, Ana18:24

 

 
Newborn Screening for Metabolic Disorders: How Are We Doing, and Where Are We Going?Bennett, Michael10:25

 

 
A Novel Technology for Measuring Cumulative Cardiac Biomarker Exposure over Time: What Happened When We Weren't Looking?deFilippi, Christopher10:43

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Growth Differentiation Factor 15: A Canary in a Coal Mine?Ho, Jennifer12:17

 

 
Impact of Biomarkers, Proteomics, and Genomics in Cardiovascular DiseaseMorrow, David7:36

 

 
Detection of Myocardial Infarction—Is It All Troponin?Hugo Katus & Mueller, Christian19:31

 

 
Diagnostic Accuracy of Plasma Glial Fibrillary Acidic Protein for Differentiating Intracerebral Hemorrhage and Cerebral Ischemia in Patients with Symptoms of Acute StrokeFoerch, Christian07:55

 

 
Absolute and Relative Kinetic Changes of High-Sensitivity Cardiac Troponin T in Acute Coronary Syndrome and in Patients with Increased Troponin in the Absence of Acute Coronary SyndromeGiannitsis, Evangelos12:23

 

 
The Challenges and Concerns Companies Face Pertaining to the US Food and Drug Administration 510(k) Process for Cardiac BiomarkersZaugg, Christian07:34

 

 
Within Sight of a Rational Pipeline for Development of Protein DiagnosticsAnderson, Leigh04:12
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Association of Growth Differentiation Factor-15 with Coronary Atherosclerosis and Mortality in a Young, Multiethnic Population: Observations from the Dallas Heart StudyRohatgi, Anand7:42
 
Markers of Plaque Instability in the Early Diagnosis and Risk Stratification of Acute Myocardial InfarctionMueller, Christian7:40
Hepcidin in Human Iron Disorders: Diagnostic ImplicationsSwinkels, Dorine10:29
Direct-to-Consumer Genetic Testing: Reliable or Risky?Spencer, David10:18
Improved Monitoring of Differences in Serial Laboratory ResultsFraser, Callum10:18
Investigating Interferences of a Whole-Blood Point-of-Care Creatinine Analyzer: Comparison to Plasma Enzymatic and Definitive Creatinine Methods in an Acute-Care SettingStraseski, Joely10:45
An About-Face for C-Reactive Protein?Szalai, Alexander14:56
Determination of Hemolysis Thresholds by the Use of Data LoggersStreichert, Thomas8:30
Preanalytical Errors Introduced by Sample-Transportation Systems:Felder, Robin6:57
Quantification of 1a,25-Dihydroxy Vitamin D by Immunoextraction and Liquid Chromatography-Tandem Mass SpectrometryHoofnagle, Andrew13:04
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